A 46-year-old man is scheduled for repair of an inguinal hernia. Six years ago, he had an episode of malignant hyperthermia during cholecystectomy. Which of the following is the most appropriate perioperative management?
(A) Administration of a regional anesthetic
(B) Administration of dantrolene orally for two days prior to surgery
(C) Avoidance of all inhalational anesthetics except isoflurane
(D) Avoidance of ester local anesthetics
(E) Flushing the anesthesia machine with oxygen 10 L/min for a minimum of 12 hours
A 60-year-old obese man who has an antithrombin III deficiency is scheduled for radical prostatectomy. Prior to the operation this patient should receive
A healthy, spontaneously breathing, supine, anesthetized patient has a PaCO2 to PetCO2 difference of 3 mmHg. Following institution of mechanical ventilation the value increases to 12 mmHg. The most likely cause of this change is
(A) cephalad displacement of the diaphragm
(B) decreased production of carbon dioxide
(C) increased cardiac output
(D) increased shunting of blood through dependent lung zones
(E) increased ventilation of nondependent lung zones
Which of the following statements concerning the choice of nitroprusside or nitroglycerin to induce deliberate hypotension is true?
(A) Nitroglycerin is more potent
(B) Nitroglycerin produces hypotension by acting on both arterial and venous capacitance vessels
(C) Nitroprusside produces less rebound hypertension on discontinuation
(D) The toxic effects of nitroprusside are independent of dose
(E) The therapeutic effects of nitroprusside may persist on discontinuation
B
A 35-year-old woman with systemic lupus erythematosus is admitted to the critical care unit following sudden onset of severe chest pain. Examination shows tachycardia, hypotension, pulmonary edema, and a blowing systolic murmur in the left parasternal region. The most appropriate management is
(A) aerosol administration of terbutaline
(B) intravenous infusion of phenylephrine and nitroglycerin
(C) intravenous infusion of esmolol
(D) intravenous infusion of epinephrine and nitroprusside
(E) volume loading with lactated Ringer's solution