10 Random Questions
The plasma concentration of an intravenously administered drug follows the two-compartment kinetic model shown in the graph. Which of the following events is illustrated by the decline in plasma concentration shown at Time #2?
- (A) Decreasing activity of the drug at its receptor site
- (B) Distribution from plasma to tissue
- (C) Elimination of the drug from plasma
- (D) Increasing volume of distribution
- (E) Redistribution from vessel-rich groups to vessel-poor groups
A sensory level of T2 is achieved after administration of spinal anesthesia. Which of the following lung volumes is LEAST likely to be affected?
- (A) Expiratory reserve volume
- (B) Inspiratory reserve volume
- (C) Inspiratory capacity
- (D) Tidal volume
- (E) Vital capacity
Which of the following statements concerning banked blood is true?
- (A) Red blood cells preserved with CPDA-1 have a shelf life of approximately 21 days
- (B) Packed red blood cells deliver oxygen normally immediately after administration
- (C) Packed red blood cells contain most of the leukocytes present in the donated unit
- (D) Citrate is used as a source of energy for whole blood
- (E) Stored whole blood contains all coagulation factors except II and VIII
Neostigmine administered intravenously without atropine can produce each of the following EXCEPT
- (A) arousal
- (B) bradycardia
- (C) bronchoconstriction
- (D) increased gastric motility
- (E) increased urinary bladder tone
Each of the following drugs increases the duration of succinylcholine action EXCEPT
- (A) echothiophate
- (B) gentamicin
- (C) magnesium sulfate
- (D) pyridostigmine
- (E) trimethaphan
Which of the following is an indication for administration of fresh frozen plasma?
- (A) Antithrombin III deficiency
- (B) Emergency antagonism of heparin effect
- (C) Hemophilia A
- (D) Transfusion of 5 units of homologous erythrocytes
- (E) Uremic coagulopathy
Which of the following statements concerning hyperkalemia after succinylcholine administration to a patient with a spinal cord injury is true?
- (A) It is unlikely to occur if the lesion is located below T6
- (B) It is unlikely to occur within 24 hours of the injury
- (C) It is unlikely to occur more than 60 days after the initial injury
- (D) It is prevented by pretreatment with small doses of a nondepolarizing agent
- (E) It is decreased in magnitude by pretreatment with calcium chloride
A 70-kg, 77-year-old man Is undergoing left nephrectomy with nitrous oxide, oxygen, fentanyl, and midazolam anesthesia. He has a 90 pack-year history of cigarette smoking and has chronic obstructive pulmonary disease. One hour after incision, expiratory wheezing occurs and peak Inspiratory pressure increases from 35 to 65 cmH20; end-tidal PCO2 is unchanged, but SpO2 decreases from 97% to 88%. The most likely cause is
- (A) endobronchial intubation
- (B) overinflation of the endotracheal tube cuff
- (C) pneumothorax
- (D) pulmonary edema
- (E) pulmonary embolism
Tingling in the fifth finger during spinal anesthesia is associated with anesthesia at which of the following dermatomes?
- (A) C4
- (B) C6
- (C) C8
- (D) T2
- (E) T4
The supine hypotensive syndrome of pregnancy
- (A) begins at 32 weeks' gestation
- (B) causes fetal distress by aortocaval compression
- (C) is corrected by Trendelenburg's position
- (D) is less likely following subarachnoid block than epidural block
- (E) occurs in 90% of supine women at 38 to 40 weeks' gestation