A 48-year-old woman with von Willebrand's disease is scheduled for a hysterectomy. The most appropriate initial preoperative therapy to decrease bleeding is administration of
A 70-kg patient is anesthetized for a craniotomy in the sitting position. Minute ventilation through a circle system is 15 L/min; PetC02 is 65 mmHg. Which of the following is the most likely cause of the increased PetC02?
One hundred children who are to have strabismus surgery are enrolled in a research protocol. Fifty receive a new antiemetic and 50 receive a placebo preoperatively. Fifteen children in the treatment group and 37 children in the control group have nausea and vomiting postoperatively. Which of the following analyses is most appropriate for determining the statistical significance of the group differences?
The duration of action of an induction dose of thiopental is determined primarily by its
The newborn infant of an 18-year-old heroin addict has an initial Apgar score of 1. After intubation of the trachea and ventilation with pure oxygen, the Apgar score is 3 at five minutes. Appropriate management at this time would include administration of each of the following EXCEPT
During use of the ventilator on an anesthesia machine, positive pressure is noted on the airway pressure gauge during exhalation. Positive end-expiratory pressure has not been purposefully added to the breathing circuit. Which of the following is the most likely cause?
Systemic hypothermia to 30°C is accompanied by
A patient with end-stage renal disease has prolonged ventilatory depression after administration of morphine. The most likely cause is increased
Which of the following is the most appropriate initial therapy for acute pulmonary hypertension with right ventricular dysfunction and severe systemic hypotension that occurs during anesthesia?
A 22-year-old woman with preeclampsia has undergone emergency cesarean delivery during general anesthesia. At the completion of the surgery, attempts at reversal of vecuronium are unsuccessful. Each of the following could be a cause of this failure EXCEPT