Anesthesia Hub -

10 Random Questions

Neuromuscular blockade of the diaphragm is best ensured by monitoring which of the following peripheral muscles?

(A) Adductor pollicis muscle
(B) First dorsal interosseous muscle
(C) Flexor hallucis muscle
(D) Muscles of the hypothenar eminence
(E) Orbicularis oculi muscle

The correlation between anesthetic potency and lipid solubility

(A) suggests that the number of molecules dissolved at the site of action causes anesthesia
(B) applies to anesthetic agents dissolved in olive oil
(C) suggests that the type of molecule causes anesthesia
(D) is consistent with the synergistic effect of anesthetics
(E) is not consistent with a unitary molecular site of action of anesthetics

A 60-year-old woman who is taking propranolol for hypertension and is allergic to penicillin is anesthetized with thiopental and halothane for resection of an abdominal aortic aneurysm. Shortly after intubation she is given vancomycin 500 mg intravenously, after which her blood pressure decreases from 140/80 to 70/50 mmHg while her heart rate remains steady at 64 bpm. The most likely explanation for the decrease in blood pressure is

(A) cross-sensitivity of penicillin and vancomycin
(B) interaction of vancomycin and propranolol
(C) vancomycin-induced anaphylactoid reaction
(D) interaction of halothane and propranolol
(E) interaction of halothane and vancomycin

Compared with midazolam, diazepam has which of the following characteristics?

(A) Greater solubility in water
(B) Shorter beta half-life
(C) More potent ventilatory depressant effect
(D) Lower risk for thrombophlebitis
(E) A pharmacologically active metabolite

BASIC Pharmacology & Pharmacokinetics

During an operation with cardiopulmonary bypass using a bubble oxygenator, the risk for systemic gas embolization increases when

(A) a filter greater than 20 microns is used in the arterial infusion tubing
(B) gas flow to the oxygenator is decreased below 3 L/min
(C) the operation is a mitral valve replacement
(D) the blood level in the oxygenator reservoir exceeds 1 liter
(E) ventricular fibrillation occurs

Which of the following statements is true concerning administration of 70% nitrous oxide to a patient with an unrecognized pneumothorax?

(A) Expansion of the pneumothorax by nitrous oxide occurs at a greater rate than expansion of bowel gas
(B) Expansion of the pneumothorax by nitrous oxide occurs at a linear rate
(C) The maximum expansion of a closed space occurs within 15 minutes
(D) The maximum concentration of nitrous oxide achievable within the pneumothorax is 35%
(E) The maximum increase in a closed gas-containing space is 100%

BASIC Pharmacology & Pharmacokinetics

Compared with a patient without liver disease, a patient with cirrhosis will have

(A) greater accumulation of vecuronium with infusion
(B) increased unbound plasma vecuronium concentration
(C) more frequent occurrence of phase II block after succinylcholine administration
(D) prolonged elimination half-life of atracurium
(E) unchanged volume of distribution for pancuronium

BASIC Pharmacology & Pharmacokinetics

A 50-year-old man is scheduled to undergo emergency craniotomy for evacuation of an epidural hematoma. His Glasgow Coma Scale score is 6; heart rate is 54 bpm, and blood pressure is 190/110 mmHg. The most appropriate initial management is administration of which of the following agents?

(A) Atropine
(B) Mannitol
(C) Nimodipine
(D) Sodium nitroprusside
(E) Thiopental

ADVANCED Neuro

In a patient with adult respiratory distress syndrome who is being mechanically ventilated, which of the following findings indicates the most severe disease?

(A) Decreased functional residual capacity
(B) Decreased lung compliance
(C) Hypercarbia
(D) Hypoxemia
(E) Increased dead space

Which of the following postoperative treatments decreases the risk for deep venous thrombosis?

(A) Blood transfusion
(B) Epidural anesthesia
(C) Etomidate
(D) Ketorolac
(E) Patient-controlled analgesia

ADVANCED General