A newly developed inhalational anesthetic has a blood-gas partition coefficient of 0.2. Which of the following statements best describes this drug compared with isoflurane?
(A) MAC is lower
(B) The difference between Fa and Fl during maintenance of anesthesia is greater
(C) Time to emergence is shorter
(D) Rapid induction requires greater overpressure
(E) Equilibrium in a circle system with the same flow of fresh gas is slower
A 50-year-old patient undergoes subtotal thyroidectomy for Graves' disease. In the immediate postoperative period, he has marked hoarseness but no stridor. The most likely cause of the hoarseness is trauma to the
(A) external branch of the superior laryngeal nerve
(B) internal branch of the superior laryngeal nerve
A 65-year-old patient with compensated congestive heart failure undergoes resection of a large tumor of the temporal lobe. During the procedure, the brain is noted to protrude through the surgical incision. After increasing minute ventila- tion, which of the following is the most appropriate next step in management?
(A) Administration of dexamethasone
(B) Administration of furosemide
(C) Administration of mannitol
(D) Induction of barbiturate coma
(E) Induction of deliberate hypotension
B
One hour after an open cholecystectomy, a 42-year-old patient is hemodynamically stable and breathing spontaneously (rate 10/min and regular) at an FiO2 of 0.4. Fentanyl, isoflurane, nitrous oxide, and pancuronium were used during the procedure. Analysis of arterial blood gases (pH, pCO2, pO2) is most likely to show:
After brachial plexus block, a patient has sensation over the inner aspect of the upper arm. Block of which of the following nerves would obtund this sensation?
A decreased dose of sodium thiopental is administered to patients in hypovolemic shock primarily because
(A) acidosis increases the fraction of unionized drug
(B) delivery of the drug to the brain is increased
(C) hepatic clearance is decreased
(D) thiopental is a myocardial depressant
(E) thiopental is a venous dilator
E
A patient is undergoing cholecystectomy with enflurane, nitrous oxide, fentanyl, and oxygen. He takes theophylline and cromolyn sodium for bronchial asthma. During skin incision he has bilateral wheezing; peak inspiratory pressure is 50 cmHzO, and the ECG shows occasional premature ventricular contractions. The most appropriate management is to