An 88-kg man is anesthetized with 66% nitrous oxide, 33% oxygen, and 1% isoflurane using a circle system. Following tracheal intubation, the nitrous oxide flow is set at 1 L/min and the oxygen flow is set at 0.5 L/min. After two hours the oxygen monitor indicates a circuit oxygen concentration of only 25% despite the flows noted above. The most likely explanation for this discrepancy is
(A) decrease of oxygen pipeline pressure to 20 psi
(B) increase in the concentration of nitrous oxide in the circuit
A 50-year-old man with an 80 pack-year history of cigarette smoking has a forced expiratory volume in one second of 1.5 L and a forced vital capacity of 3.5 L. Which of the following statements concerning intraoperative anesthetic management is true?
(A) An I:E ratio of 1:1 will improve carbon dioxide removal more than an I:E ratio of 1:2.5
(B) Antagonism of neuromuscular block will most likely trigger acute bronchospasm
(C) Functional residual capacity will increase during an acute exacerbation of bronchospasm
(D) Induction with ketamine will increase airway resistance