Anesthesia Hub -

10 Random Questions

The decreased duration of action of an intravenous dose of fentanyl compared with an intravenous dose of morphine is best explained by

(A) greater lipid solubility
(B) increased hepatic metabolism
(C) less protein binding
(D) shorter elimination half-life
(E) smaller volume of distribution

BASIC Pharmacology & Pharmacokinetics

Which of the following statements concerning the volume of distribution of a drug is true?

(A) It is equal to the sum of the volumes of the tissue spaces into which it diffuses
(B) It is equal to the volume to which it is distributed outside the plasma volume
(C) It is unaltered by the amount bound to red blood cells and plasma proteins
(D) It depends on elimination from plasma
(E) It relates the total amount of the drug in the body to the plasma concentration

BASIC Pharmacology & Pharmacokinetics

After inflation of both the tracheal and endobronchial cuffs of a left-sided double-lumen tube, the following are noted on auscultation of the chest: Left lumen clamped --> Breath sounds absent bilaterally; Right lumen clamped --> Breath sounds present on left only; Both lumens open --> Breath sounds present on left only. The most appropriate action is to

(A) decrease the endobronchial cuff volume
(B) decrease the tracheal cuff volume
(C) reinsert the tube, rotating it 180 degrees to the right
(D) suction both lumens
(E) withdraw the tube slightly and repeat the auscultory maneuvers

BASIC Equipment & Physics

Which of the following is the most likely effect of infrarenal cross clamping of the aorta without pharmacologic manipulation?

(A) Decreased cardiac output
(B) Decreased pulmonary artery occlusion pressure
(C) Increased left ventricular stroke volume
(D) Increased renal blood flow
(E) Improved myocardial oxygen supply-demand ratio

ADVANCED General

Which of the following is the most important function of temperature compensation in anesthetic vaporizers?

(A) Compensation for changes in the specific heat of the anesthetic during vaporization
(B) Delivery of diluent gas at a constant temperature regardless of flow rate
(C) Increase of bypass flow when the vaporizer is cooled by high fresh gas flow
(D) Maintenance of constant anesthetic vapor output over a range of vaporizer temperatures
(E) Maintenance of constant vapor concentrations at low flow rates

BASIC Equipment & Physics

Meperidine has a more rapid onset of action than morphine following intravenous injection because of its

(A) lesser ionization
(B) greater lipid solubility
(C) lesser protein binding
(D) smaller volume of distribution
(E) slower rate of hepatic clearance

BASIC Pharmacology & Pharmacokinetics

Compared with a patient who is breathing spontaneously, a patient in the supine position receiving controlled positive-pressure ventilation will most likely have which of the following findings?

(A) Decreased pulmonary vascular resistance
(B) Decreased ratio of dead space to tidal volume
(C) Increased ventilation of nondependent alveoli
(D) Increased perfusion of nondependent alveoli
(E) Improved matching of ventilation to perfusion

BASIC Respiratory & Critical Care

A 55-year-old woman receiving chronic dialysis for renal failure comes to the emergency department with a perforated viscus. She has chest pain. Heart rate is 124 bpm, blood pressure is 90/60 mmHg, and respiratory rate is 18/min. Surgery is to be performed within the hour. Which of the following best describes this patient's ASA physical status classification?

(A) III
(B) III E
(C) IV
(D) IV E
(E) V E

Which of the following processes is primarily responsible for the decrease in core body temperature that occurs during the first hour of general anesthesia?

(A) Decreased production of heat
(B) Convective heat loss caused by cutaneous vasodilation
(C) Evaporative heat loss during skin preparation
(D) Heat loss from the respiratory tract
(E) Redistribution of core body heat to the periphery

BASIC General

One full E-cylinder of oxygen at 20°C can deliver 2 L/min of oxygen for at most

(A) 30 minutes
(B) 90 minutes
(C) 3 hours
(D) 5 hours
(E) 12 hours

BASIC Equipment & Physics