Compared with the demand-flow intermittent mandatory ventilation (IMV) system, the continuous-flow IMV system has which of the following characteristics?
(A) It cannot be used with positive end-expiratory pressure
(B) It permits monitoring of exhaled tidal volume
(C) It decreases waste of medical gases
(D) It decreases the work of breathing
(E) It synchronizes mechanical and spontaneous breaths
D
In a patient with 20% pulmonary shunt and a PaO2 of 60 mmHg, cardiac output suddenly decreases from 5 L/min to 3 L/min. Oxygen consumption is unchanged. As a result, the PaO2 will
(A) increase slightly because of decreased shunt blood flow
(B) decrease slightly because of decreased mixed venous PO2
(C) increase because of decreased affinity of hemoglobin for oxygen
(D) decrease because of an increased dead space to tidal volume ratio
(E) increase because of increased pulmonary oxygen uptake per milliliter of blood
In an anesthetized patient being mechanically ventilated, end-expired carbon dioxide is 58 mmHg and peak inspiratory airway pressure is 15 cmH20. Ventilator settings indicate a delivered tidal volume of 800 ml, but the expiratory flowmeter shows a tidal volume of 360 ml. Which of the following is the most likely cause of this discrepancy?
(A) Fresh gas flow of 0.5 L/min
(B) Incompetence of the pressure-relief valve
(C) Low ventilatory rate
(D) Presence of a hole in the ventilator bellows
(E) Prolongation of the inspiratory phase
B
Which of the following is characteristic of soda lime and Baralyme carbon dioxide absorption canisters used in circle systems?
(A) Calcium carbonate is a major end product
(B) Carbon dioxide absorption cools the anesthetic gases
(C) Flushing the canister with oxygen for six hours will regenerate 50% of the spent Baralyme
(D) Gases lose water vapor as they pass through the canisters
(E) Soda lime and Baralyme depend on silica as a binding agent
A 65-year-old man with essential hypertension well controlled around 140/90 mmHg with hydrochlorothiazide is scheduled for right colectomy for carcinoma. Preoperative EKG and all laboratory values are normal except for a hematocrit of 29% and serum potassium level of 3.2 mEq/L. Central venous pressure (CVP) measured from an internal jugular catheter inserted before induction of anesthesia is 7 mmHg. Ten minutes after induction with thiopental 200 mg followed by enflurane 3% in nitrous oxide and oxygen (50% each), blood pressure decreases suddenly from 110/70 to 80/50 mmHg with heart rate unchanged at 78 bpm. CVP is now 20 mmHg and the EKG demonstrates a midjunctional rhythm. After discontinuing the enflurane, the most appropriate action would be to
(A) administer furosemide 20 mg intravenously
(B) verify proper placement of the CVP catheter
(C) administer atropine 0.4 mg intravenously
(D) administer packed erythrocytes 1 unit
(E) administer potassium 20 mEq in 250 ml of intravenous fluid over 15 minutes
The plasma concentration of an intravenously administered drug follows the two-compartment kinetic model shown in the graph. Which of the following events is illustrated by the decline in plasma concentration shown at Time #2?
(A) Decreasing activity of the drug at its receptor site
(B) Distribution from plasma to tissue
(C) Elimination of the drug from plasma
(D) Increasing volume of distribution
(E) Redistribution from vessel-rich groups to vessel-poor groups