10 Random Questions
When compared with diazepam, midazolam
- (A) metabolites contribute more significantly to the sedative effect
- (B) elimination is less dependent on hepatic metabolism
- (C) has more predictable action after intramuscular administration
- (D) produces less respiratory depression
- (E) produces less hypotension during induction of anesthesia with opioids
Which of the following is the most common cause of coagulopathy occurring during massive blood transfusion?
- (A) Decreased serum fibrinogen concentration
- (B) Decreased serum ionized calcium concentration
- (C) Dilutional thrombocytopenia
- (D) Disseminated intravascular coagulation
- (E) Hypothermia
The test dose of local anesthetic administered through an epidural needle or catheter should be sufficient to produce
- (A) bradycardia
- (B) seizure activity
- (C) hypotension
- (D) segmental analgesia
- (E) spinal anesthesia
BASIC
OB
Regional & Pain
In a patient with chronic congestive heart failure, the safest pharmacologic approach to brain swelling during a craniotomy is
- (A) dexamethasone
- (B) furosemide
- (C) mannitol
- (D) thiopental
- (E) urea
During apneic oxygenation (FiO2 1.0) through a rigid bronchoscope
- (A) duration of the procedure is limited by the increase in PaCO2
- (B) functional residual capacity decreases 5%/min
- (C) PaO2 remains unchanged for the first 5 minutes
- (D) PaCO2 increases 2 to 6 mmHg/min for 15 minutes and then reaches a plateau
- (E) PaO2 and PaCO2 equilibrate with mixed venous gases at the same rate
BASIC
Respiratory & Critical Care
Which of the following conditions is a contraindication to the use of succinylcholine?
- (A) Burns of 50% body surface area occurring 12 hours ago
- (B) Cirrhosis
- (C) Myotonic dystrophy
- (D) Seizure disorder
- (E) Spinal cord transection within the past six hours
ADVANCED
Pharmacology & Pharmacokinetics
If minute ventilation is held constant, which of the following is LEAST likely to alter PaCO2?
- (A) General anesthesia
- (B) Hypothermia
- (C) Increased dead space
- (D) Increased pulmonary shunt
- (E) Induced hypotension
BASIC
Respiratory & Critical Care
When the inspired gas is changed from air to 20% oxygen and 80% nitrous oxide, PaO2 increases because
- (A) increased pulmonary artery pressure perfuses alveoli that previously enhanced dead space
- (B) nitrous oxide stimulates the respiratory center
- (C) rapid absorption of nitrous oxide increases alveolar oxygen concentration
- (D) replacement of nitrogen by nitrous oxide expands atelectatic alveoli
- (E) respiratory depression from nitrous oxide shifts the oxyhemoglobin dissociation curve
BASIC
Pharmacology & Pharmacokinetics
If both recurrent laryngeal nerves were severed during a difficult thyroidectomy for cancer, the most likely finding would be
- {A) paralysis of the cricothyroid muscles
- (B) cadaveric positioning of the true vocal cords
- (C) anesthesia of both sides of the epiglottis
- (D) bilateral pure adductor vocal cord paralysis
- (E) stridor
ADVANCED
Regional & Pain
Which of the following laboratory studies is the best indicator of reversal of the effects of warfarin?
- (A) Activated clotting time
- (B) Activated partial thromboplastin time
- (C) Bleeding time
- (D) Plasma fibrinogen concentration
- (E) Prothrombin time
BASIC
Pharmacology & Pharmacokinetics