58 questions match your search.


Administration of succinylcholine 1 mg/kg to a pregnant woman rarely causes fetal neuromuscular blockade. Which characteristic of succinylcholine best explains this phenomenon?

ADVANCED Pharmacology & Pharmacokinetics OB

Hyperkalemia in response to the administration of an intubating dose of succinylcholine is associated with each of the following disorders EXCEPT

ADVANCED Pharmacology & Pharmacokinetics

A 64-year-old, 70-kg woman treated with lithium for manic-depressive psychosis is given methohexital 90 mg and succinylcholine 35 mg intravenously for electroconvulsive therapy. Ten minutes later she remains sedated and the peripheral nerve stimulator shows a decreased twitch response. The most likely explanation is

ADVANCED Pharmacology & Pharmacokinetics

A patient has tonic movements of the head and neck, nystagmus, and slurred speech after receiving metoclopramide for nausea after nitrous oxide-opioid anesthesia. The most appropriate pharmacologic treatment is

ADVANCED Pharmacology & Pharmacokinetics

After termination of cardiopulmonary bypass, a patient who is chronically digitalized receives digoxin 0.5 mg in error. An ECG shows sinus bradycardia with intermittent sinus arrest; blood pressure is 90/60 mmHg. Which of the following drugs is contraiindicated in this patient?

ADVANCED Pharmacology & Pharmacokinetics Cardiac

A complication of terbutaline therapy to terminate premature labor is

ADVANCED Pharmacology & Pharmacokinetics OB

Which of the following conditions is a contraindication to the use of succinylcholine?

ADVANCED Pharmacology & Pharmacokinetics

The alveolar concentrations of anesthetics increase more rapidly in children than in adults because of a greater

ADVANCED Pharmacology & Pharmacokinetics Pediatric

Inhibition of labor by terbutaline causes each of the following maternal side effects EXCEPT

ADVANCED Pharmacology & Pharmacokinetics OB

A 76-year-old patient is restless and hallucinating in the preoperative holding area. He received morphine 5 mg and scopolamine 0.4 mg intramuscularly as premedication and is now breathing oxygen 2 L/min through nasal prongs. SpO2 is 98%. Which of the following is the most appropriate next step?

ADVANCED Pharmacology & Pharmacokinetics

A previously healthy 28-year-old woman scheduled for laparoscopic tubal ligation becomes, agitated and refuses to undergo the procedure after being brought to the operating room. This behavior most likely resulted from preoperative administration of

ADVANCED Pharmacology & Pharmacokinetics General

A 65-year-old patient receiving long-term clonidine therapy fails to take it one day before surgery. This would most likely

ADVANCED Pharmacology & Pharmacokinetics

Prilocaine is NOT recommended for obstetric regional anesthesia because it

ADVANCED Pharmacology & Pharmacokinetics OB

Anesthesia is induced with halothane in a 3-year-old girl. Sixty seconds after administration of succinylcholine 1 mg/kg intravenously, heart rate decreases rapidly from 120 to 60 bpm. The most likely cause is

ADVANCED Pharmacology & Pharmacokinetics Pediatric

During therapy for eclampsia, toxic blood levels of magnesium sulfate can be distinguished from therapeutic levels by the presence of

ADVANCED Pharmacology & Pharmacokinetics OB

Each of the following is a recognized complication during a transurethral resection for which glycine is used as an irrigant EXCEPT

ADVANCED Pharmacology & Pharmacokinetics General

Miosis, incontinence, excess salivation, and convulsions are toxic effects of

ADVANCED Pharmacology & Pharmacokinetics

One week after sustaining third-degree burns over 40% of his body surface area, a patient requires general anesthesia for debridement and skin grafting. Which of the following responses to neuromuscular blockers is most likely?

ADVANCED Pharmacology & Pharmacokinetics

When succinylcholine is administered intravenously to infants, intragastric pressure

ADVANCED Pharmacology & Pharmacokinetics Pediatric

A 70-year-old man who has just undergone an abdominal aortic aneurysm repair under halothane anesthesia develops hypertension, dyspnea, and cyanosis shortly after awakening in the recovery room. Administration of furosemide 20 mg intravenously improves the cyanosis within 10 minutes. This immediate effect of furosemide is best explained by

ADVANCED Pharmacology & Pharmacokinetics General

Metoclopramide

ADVANCED Pharmacology & Pharmacokinetics

The low fetal/maternal plasma ratio of bupivacaine compared with lidocaine is due to

ADVANCED OB Pharmacology & Pharmacokinetics

A 64-year-old man with diabetes mellitus well controlled with NPH insulin undergoes lower extremity revascularization. Following administration of protamine 10 mg, the patient has facial flushing and blood pressure of 60/30 mmHg. The most appropriate initial step in management is administration of which of the following drugs?

ADVANCED Pharmacology & Pharmacokinetics General

Which of the following statements concerning neuroleptic malignant syndrome is true?

ADVANCED Pharmacology & Pharmacokinetics General

A 23-year-old man who is receiving his first anesthetic has not resumed spontaneous ventilation two hours after receiving succinylcholine. The train-of-four monitor shows no twitch response. Which of the following is the most likely cholinesterase genotype in this patient?

ADVANCED Pharmacology & Pharmacokinetics General

Following protamine administration, profound pulmonary hypertension is most likely initiated by release of

ADVANCED Pharmacology & Pharmacokinetics Cardiac

The effect of neomycin at the neuromuscular junction is

ADVANCED Pharmacology & Pharmacokinetics

A 15-kg, 3-year-old child is anesthetized for an inguinal hernia repair with halothane and nitrous oxide. The trachea is intubated after administration of succinylcholine 30 mg. At the conclusion of the 45-minute procedure, the child is not breathing; a peripheral nerve twitch monitor indicates no response to a train-of-four stimulus. Further investigation is most likely to show

ADVANCED Pharmacology & Pharmacokinetics Pediatric

Each of the following is consistent with exposure to organophosphates EXCEPT

ADVANCED Pharmacology & Pharmacokinetics

In treating arterial hypertension in a patient with a head injury, the agent LEAST likely to increase intracranial pressure is

ADVANCED Pharmacology & Pharmacokinetics Neuro

Each of the following is an effect of rapid infusion of mannitol EXCEPT

ADVANCED Pharmacology & Pharmacokinetics Neuro

Intravenous administration of mannitol during a craniotomy

ADVANCED Pharmacology & Pharmacokinetics Neuro

Which of the following is associated with the application of a transdermal fentanyl patch?

ADVANCED Pharmacology & Pharmacokinetics Regional & Pain

The following hemodynamic values are obtained two hours after coronary artery bypass surgery: Cardiac index 1.7 L/min/m2; Pulm Art. Occ. Pressure 22 mmHg; MAP 60 mmHg; Urine volume 0.2 ml/kg/hr. The most appropriate management is

ADVANCED Pharmacology & Pharmacokinetics Cardiac

The physiologic function most likely to be spared when a local anesthetic differential nerve block is administered is

ADVANCED Pharmacology & Pharmacokinetics Regional & Pain

In a patient who is to undergo clipping of a cerebral aneurysm, an advantage of isoflurane over nitroprusside for induction of hypotension is

ADVANCED Pharmacology & Pharmacokinetics Neuro

A 55-kg, 70-year-old woman with mild chronic renal failure is unresponsive 20 hours after an uneventful coronary artery bypass grafting procedure. Anesthetic drugs included fentanyl 3000 mcg, diazepam 35 mg, and pancuronium 20 mg. Which of the following is the most appropriate next step in management?

ADVANCED Pharmacology & Pharmacokinetics Cardiac

The induction dose of thiopental should be decreased in each of the following situations EXCEPT

ADVANCED Pharmacology & Pharmacokinetics

Which of the following would be most likely to increase the duration of seizures during electroconvulsive therapy using a barbiturate and succinyleholine for general anesthesia?

ADVANCED Pharmacology & Pharmacokinetics Neuro

The concentration of bupivacaine is higher in maternal blood than in fetal blood because

ADVANCED Pharmacology & Pharmacokinetics OB

A 35-year-old woman with a grade III subarachnoid hemorrhage is undergoing clipping of a middle cerebral artery aneurysm 48 hours after initial hemorrhage. Which of the following drugs used to induce hypotension is LEAST likely to affect intracranial pressure?

ADVANCED Pharmacology & Pharmacokinetics Neuro

Compared with epidural administration of hydrophilic opioids, epidural administration of lipophilic opioids is associated with

ADVANCED Pharmacology & Pharmacokinetics Regional & Pain

Which of the following drugs is LEAST likely to cross the placenta?

ADVANCED Pharmacology & Pharmacokinetics OB

Which of the following drugs exerts a vasoconstrictor effect by blocking the reuptake of norepinephrine at the neuronal synapse?

ADVANCED Pharmacology & Pharmacokinetics

Each of the following improves coagulation in patients with uremia EXCEPT

ADVANCED Pharmacology & Pharmacokinetics General

In a patient who is receiving nitroglycerin intravenously after a coronary artery operation, peripheral oxygen saturation is 85% and PaO2 is 200 mmHg. The most appropriate management is administration of

ADVANCED Pharmacology & Pharmacokinetics

Inhalation induction of anesthesia is more rapid in a 6-month-old infant than in an adult because infants have

ADVANCED Pharmacology & Pharmacokinetics Pediatric

Compared with similar use in adults, routine use of succinylcholine in children is hazardous because of the increased risk for which of the following?

ADVANCED Pharmacology & Pharmacokinetics Pediatric

Each of the following is an effect of acute preoperative oral administration of clonidine EXCEPT

ADVANCED Pharmacology & Pharmacokinetics

A patient receiving monoamine oxidase inhibitor therapy for depression undergoes an emergency cholecystectomy. Which of the following is the best means of providing postoperative analgesia in this patient?

ADVANCED Pharmacology & Pharmacokinetics Regional & Pain

Each of the following is an adverse effect of ritodrine used for suppression of labor EXCEPT

ADVANCED Pharmacology & Pharmacokinetics OB

In the diagram, point "X" represents a patient with severe left ventricular dysfunction. The points labeled 1, 2, and 3 each represent the results of a different therapeutic intervention. Which of the following represents the most likely intervention at each point?

ADVANCED Pharmacology & Pharmacokinetics Cardiac

Succinylcholine can be administered safely to a patient with

ADVANCED Pharmacology & Pharmacokinetics

Dantrolene

ADVANCED Pharmacology & Pharmacokinetics

Which of the following is an effect of acetazolamide?

ADVANCED Pharmacology & Pharmacokinetics

Each of the following is a characteristic of prostaglandin E1 (alprostadil) pharmacology in an infant EXCEPT:

ADVANCED Pharmacology & Pharmacokinetics Pediatric

Each of the following would be expected after preoperative oral administration of clonidine EXCEPT

ADVANCED Pharmacology & Pharmacokinetics

Which of the following drugs administered to a parturient eliminates fetal heart rate variability?

ADVANCED Pharmacology & Pharmacokinetics OB